Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. The use of Injectafer and Feraheme in treating IDA in these adults has been directly compared in a clinical study. Can diet help improve depression symptoms? Injectafer and Venofer are both brand-name drugs. In pediatric patients the most common side effects (>2%) are headache, viral respiratory tract infection, peritonitis, upset stomach, throwing up, fever, dizziness, cough, arteriovenous fistula thrombosis, hypotension and hypertension (increased blood pressure). No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. Injectafer and Feraheme are both brand-name drugs. 3 0 obj Others last much longer (even a lifetime), which can be quite traumatizing to people. The iron released by this drug does pass into human breast milk. Some products that may interact with this drug include: vitamin products, other iron-containing products. And babies born to those who took Injectafer during pregnancy didnt have any major congenital anomalies (also sometimes called birth defects). The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. generalized weakness. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. This is why family members often have the same issues with drugs as others in theirfamily. In clinical studies, people who took Injectafer still had iron in their system that was released by the drug 24 days after theyd gotten their injection. Its not known how often people taking a treatment other than Injectafer had diarrhea. Symptoms include shock, dangerously low blood pressure, loss of consciousness, and/or collapse. Examples of other drugs that may be used to treat IDA include: Your doctor will recommend the drug thats right for you depending on the severity of your anemia and any other medical conditions you may have. Common side effects of Venofer include: muscle cramps, nausea, vomiting, stomach pain, strange taste in the mouth or decreased sense of taste, diarrhea, constipation, headache, cough, sore throat, sinus pain, congestion, back pain, joint pain, dizziness, weakness, tired feeling, anxiety, ear pain, swelling of the arms/legs, or Venofer also comes as a liquid thats given by either IV infusion or a slow IV injection. But they wont receive a total cumulative dose of more than 1,500 mg of Injectafer. Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. Some people may also experience skin irritation from the adhesive tape and other medical equipment used during the procedure. People with IDA have low blood levels of hemoglobin. One of the most commonly used tests to monitor IDA is the hemoglobin test. experience severe side effects, please seek medical attention right away and notify the ordering physician. pain or burning at the injection site. Drug interactions may change how your medications work or increase your risk for serious side effects. This information is not specific medical advice and does not replace information you receive from the healthcare provider. Call your doctor for instructions if you miss an appointment for your Venofer injection. Why is the range so wide? If the underlying cause of your anemia isnt addressed, theres a chance your anemia could come back after Injectafer treatment. Keep in mind that there may be additional costs related to getting your doses of the drug at a medical facility. Injectafer isnt available in a generic form. The drug helps increase your hemoglobin level back to a value thats within the normal range. Hemoglobin is a protein thats found inside your red blood cells. But if they become more severe or dont go away, talk with your doctor or pharmacist. Venofer 100 mg iron/5 mL intravenous solution, Venofer 50 mg iron/2.5 mL intravenous solution, Venofer 200 mg iron/10 mL intravenous solution, Select a condition to view a list of medication options. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Do not share your drugs with others and do not take anyone else's drugs. *Patients are calculated based on an estimated annual cumulative dose. Remember that it is best to get your vitamins and minerals from food whenever possible. An iron infusion is a way to increase the body's iron levels quickly. intense abdominal pain. Tell your doctor about the allergy and what signs you had. With IV infusion, the drug is given as a slow drip into your vein over a period of time. Its not known if Injectafer is safe to take during pregnancy. Its not currently available in generic form. Possibleside effectsareweight gainand suicidal thoughts. Potential side effects that are usually mild may include, but are not limited to: Headache Nausea Dry Mouth Stomachache Dizziness Diarrhea Constipation These side effects may not impact life too much and may only be temporary. Theyll likely have you stop taking the pills while youre using Injectafer. The benefit of treating your condition during pregnancy may outweigh any risks. Have blood work checked as you have been told by the doctor. This information should not be used to decide whether or not to take Venofer or any other medicine. Venofer is for use in adults and children at least 2 years old. Serious side effects from Injectafer arent common, but they can occur. Drug interactions: DayQuil can interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. Available for Android and iOS devices. Side effects from HRT depend on a number of factors: Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. If either is present, do not use the liquid. Its possible to get rid of or reduce the severity ofside effects. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. Iron sucrose can also be mixed in a. With anemia, you have a low level of red blood cells (RBCs) in your body. If you have a severe allergic reaction to Injectafer after youve left the medical facility where you received your dose of the drug, call your doctor right away. They can recommend if this is safe for you to do. But in some people, Injectafer can cause symptoms of hypophosphatemia to occur. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. . Talk with your doctor. You will need to talk about the benefits and risks to you and the baby. Learn more about the types of tests and treatment. Some drugs may have another patient information leaflet. But you dont necessarily need to eat these foods unless your doctor tells you to do so. Iron is an essential nutrient needed to maintain energy levels and keep you healthy. If you have iron deficiency anemia (IDA), consuming moderate amounts of alcohol may be safe, if your doctor tells you its OK. (With IDA, you have a low level of red blood cells thats caused by not having enough iron.). chest pain. Your doctor will go over your In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). Hypophosphatemia seems to mostly occur in people who are already at risk for low phosphorus levels. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. If you have questions about side effects, call your doctor. However, since peoples bodies react so differently to drugs, they often have to change their stance on certaindrugs. (A generic drug is an exact copy of the active drug in a brand-name medication.) Brand-name medications usually cost more than generics. Instead, youll start by receiving just one treatment course of Injectafer. Diarrhea. Venofer may cause significant hypotension (decreased blood pressure). Nose or throat irritation. Phosphorus also helps your nerves function properly. VenAccess is a trademark of Vifor (International) Inc. Switzerland. US residents can call their local poison control center at 1-800-222-1222. Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). With IDA, you have low hemoglobin levels. These symptoms can include: While youre taking Injectafer, your doctor will monitor your phosphorus levels if youre at risk for hypophosphatemia. Before using, check this product visually for particles or discoloration. It is very important that your doctor check you closely while you are receiving this medicine. The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. Then your body uses that iron to make hemoglobin and RBCs. Maximum concentrations of Injectafer are achieved within 15 minutes to 1.21 hours following administration. 2. This product may contain inactive ingredients, which can cause allergic reactions or other problems. (One treatment course includes two doses of the drug.) It can also cause skin irritation and redness. Headache. However, Injectafer has been studied for use in children with iron deficiency anemia (IDA). Feraheme is also approved to treat IDA in adults who either didnt have improvement in their IDA or had side effects with iron treatment thats taken by mouth. Data on file, American Regent, Inc. 1. These lists dont include all possible side effects. endobj Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. One class of immune checkpoint inhibitors targets the protein PD-1, which acts as a brake to keep the immune system in check. This includes your doctors, nurses, pharmacists, and dentists. Theseeffects of medicine on thebodycan also lead to medication non-compliance and worsening of themedical conditionthey are meant to treat. This hormone is made by your kidneys. Generic name: iron sucrose (injection) [EYE-urn-SOO-krose] Maintain a well-balanced diet, and follow any dietary guidelines as directed by your doctor. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. They can tell you about other medications that may work well for you. Do not flush down a toilet or pour down a drain unless you are told to do so. endobj (And Injectafer is used to treat IDA.) Iron-refractory iron deficiency anemia (IRIDA) is a genetic form of anemia. You may need extra iron because of blood loss during kidney dialysis. Read all information given to you. Otherwise, call a poison control center right away. Source: Wolters Kluwer Health. endobj Allergic reactions typically occur the first time your body is exposed to a drug. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. Injectafer comes as a liquid solution inside vials. However, some people may have weight changes as they have improvement in their anemia, which Injectafer is used to treat. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. HRT, like other medications, does have some side effects and these are thought to be quite common. If youre wondering how longside effectslast, youll be happy to know they can last just a few hours. Nausea. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. Yes, in some cases it may. The researchers looked to see how well each drug worked to increase peoples hemoglobin level. If your symptoms or health problems do not get better or if they become worse, call your doctor. Side effectswill last a very long time if the cause of them is not resolved. If you notice other effects not listed above, contact your doctor or pharmacist. The following information is provided for clinicians and other healthcare professionals. Also tell them about any vitamins, herbs, and supplements you use. Procedure Details Tell your doctor if you are pregnant or plan to become pregnant. However, be sure to take the dosage your doctor prescribes for you. If you are using this medication at home, learn all preparation and usage instructions from your health care professional. If youre not sure if youll need to get prior authorization for Injectafer, contact your insurance company. An example of a drug interaction that many people are not aware of isgrapefruitjuice and statins. These include: Note: For more information about the potential negative effects of Injectafer, see the Injectafer side effects section above. fluid retention, especially in your arms, legs, or feet, people who took Feraheme had their hemoglobin level increase, on average, by 1.38 grams per deciliter (g/dL), people who took ferric carboxymaltose had their hemoglobin level increase, on average, by 1.63 g/dL, having strange cravings to eat items that arent food, such as ice, people who took Injectafer had their hemoglobin level increase, on average, by 1.6 grams per deciliter (g/dL), people who kept taking iron by mouth had their hemoglobin level increase, on average, by 0.8 g/dL, people who took Injectafer had their hemoglobin level increase, on average, by 2.9 g/dL, people who took the other intravenous iron product had their hemoglobin level increase, on average, by 2.2 g/dL, people who took Injectafer had their hemoglobin level increase by an average of 1.1 g/dL, people who took Venofer had their hemoglobin level increase by an average of 0.9 g/dL, cannot tolerate or have shown a poor response to oral iron, or, have been diagnosed with chronic kidney disease (CKD) that is non-dialysis dependent. WebMD does not provide medical advice, diagnosis or treatment. With CKD, your kidneys dont function properly, which can lead to your body having problems using iron. These are not all of the side effects that may occur. Dilute Venofer in a maximum of 250 mL of 0.9% NaCl. This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. Most people will metabolize medication by half every time it circulates the body. If youre taking iron pills, be sure to tell your doctor before starting Injectafer. In one study, treatment with Injectafer was compared with that of iron thats taken by mouth. Call your doctor for medical advice about side effects. Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. These tests will help make sure Injectafer is working to treat your iron deficiency anemia (IDA). In clinical trials,. In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. Then the study was split into the following two groups, which are discussed below. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. They can recommend appropriate treatment options. Do not exceed 1,500 mg of iron per dosing course. This way, if you have an allergic reaction to Injectafer, your healthcare professional can treat your reaction. On day three I had a headache and felt heavy/exhausted, which lasted a few days. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. But its important to note that these studies werent designed to show whether Injectafer is safe to use during pregnancy. You may report side effects to the FDA at 1-800-332-1088. Check with your pharmacist if you have questions about the best way to throw out drugs. Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. I hope you found answers and are feeling better now. Venofer is given as an infusion into a vein. With slow IV injection, the drug is given as a single, slow injection into your vein. You should not receive Venofer if you have known allergies to iron sucrose. Call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. But even if youre not at risk for the condition, your doctor may still monitor your phosphorus levels. <> This gives a total cumulative dose of 1,500 mg of Injectafer. Orofer S 50 Injection 1 Injection in 1 Packet 147. And this could lead to weight gain, if they increase their food intake. Pain, swelling, or redness at the injection site may occur. The Injectafer dosage your doctor prescribes will depend on your body weight. I actually was constipated after my 3rd but didn't think anything of it. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. Your doctor may also recommend that you take iron supplements by mouth (if you havent tried these supplements in the past). Common Venofer side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting, diarrhea; muscle or joint pain, back pain; pain or swelling in an arm or leg; itching; or bruising or irritation where the medicine was injected. Theseside effectsmay last as long as they are undercancer treatment. <> Tell your caregivers right away if you have: problems with your dialysis vein access point; high blood pressure - severe headache, blurred vision, pounding in your neck or ears; low blood pressure - a light-headed feeling, like you might pass out; or. Tell your doctor if you are taking iron supplements or other iron-based oral medications. And theyll recommend how soon after starting the drug you need to have this level checked. For example, if someone takes 100 mg of a drug, only half of it will be in the bloodstream in a couple ofhours. All rights reserved. If you have questions about using Injectafer in a child, talk with your doctor. Common MRI side effects include dizziness, anxiety, headache, nausea, hearing loud noises, and feeling chilled or hot in the MRI scanner. Examples of these side effects include dizziness and nausea. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. endobj Not all possible drug interactions are listed here. In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. If you notice any changes to your normal blood pressure, call your doctor right away. This includes people who: Usually, hypophosphatemia doesnt cause symptoms. Iron infusion benefits. The potential side effects of Daxxify are nearly identical to that of Botox bruising, headaches, and droopy eyelids with one big difference: They could last longer. Find comprehensive medical information for Venofer intravenous on RxList including its uses, side effects, precautions, drug interactions, overdose, pill images & warnings . Your doctor will monitor your hemoglobin level to tell if Injectafer is working for you. Injectafer can be exposed to temperatures between 59F to 86F (15C to 30F) for a short period of time. It may also cause nervousness, restlessness, and difficulty sleeping in some people. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Iron sucrose can harm an unborn baby if you have a severe reaction to this medicine during your second or third trimester. Low blood pressure. Heres some detail on certain side effects this drug may cause. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. A lack of iron can lead to iron deficiency anaemia if left untreated. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. signs of inflammation in the lining of your stomach - pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. Injectafer can cause mild or serious side effects. In severe cases, it can cause asthma-like symptoms, such as wheezing and difficulty breathing. These people may lose weight as their anemia improves because theyre more active. Do not start, stop, or change the dose of any drug without checking with your doctor. Injectafer is a brand-name prescription drug. All of the people took iron by mouth for 2 weeks. Side effects like nausea and low blood pressure are common with most iron infusions. Injectafer contains the active drug ferric carboxymaltose. People who are ongoingcancer treatmentwithradiation therapyor takingchemotherapy drugsmay be more susceptible toside effects. fever, cold or flu symptoms (sore throat, cough, stuffy nose, sneezing); bruising or irritation where the medicine was injected. Its not known whether its safe to breastfeed while youre taking Injectafer. This medication is given by injection into a vein as directed by your doctor. XAO$$d|0tX1`Q$Il#FBm}{#h!/;[bOvvg7 ?tMl7/+wya^,~PA}6&Ftb19OeJ6-a3acKjcpkeGq+7/nO AJJ:Okyfp;xw|]McmK?9"t0m%. With this condition, you also have a low hemoglobin level. 4 0 obj For reasons we dont fully understand, some peoples immune system gets over-activated when the drug enters their body. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. These effects typically last between 7 and 11 hours. Your doctor will do laboratory tests to monitor your response. After receiving IV iron therapy, you will be monitored for 30 minutes to make sure you do not have an allergic reaction or a drop in blood pressure. Symptoms of overdosage include drowsiness, mental confusion, dizziness, diarrhea and vomiting etc. Depending on your doctors instructions and If you have symptoms of a low phosphorus level, call your doctor. fever. You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. What are the side effects of Venofer? Consult the product instructions and your pharmacist for storage details. However, since peoples bodies react so differently to drugs, they often have to change their stance on certain drugs. Notify your healthcare provider of any irritation at the injection site. Dizziness. It will take about three weeks to feel the effects but your fatigue will disappear and you will feel like a new person. It belongs to a class of medications known as iron replacement products. These nutrients include iron, vitamin B12, and folate. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. Below are examples of these side effects. Side effects are uncomfortable reactions to medications or drugs. After 5 weeks of treatment: This study didnt determine if either drug was better than the other. What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. Constipation,dry mouth, headaches, upset stomach, and many othercommonside effectscan greatly affect peoples quality of life, though. Allergic reaction As with most drugs, some people can have an allergic reaction after taking Injectafer. Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. Learn about uses, cost, how it works, and more. Details. With a delayed reaction, your body reacts to a drug that youve been exposed to in the past without having a reaction. How is Venofer (iron sucrose) given? reactions at the site of the injection. This document does not contain all possible drug interactions. Its possible that after getting two doses of Injectafer, your anemia may go away completely. What Is the Cost of Whole Genome Sequencing (WGS)? reese0809 1 yr. ago. Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. Both Injectafer and Feraheme belong to a class of medications known as iron replacement products. Taking a larger dose of LSD can extend the duration of the trip, but generally, the main effects of LSD don't tend to last any longer than 12 hours. Notify your healthcare provider if you are pregnant, or planning to get pregnant or breastfeeding. Venofer (iron sucrose) is given as an injection into the veins (intravenously or IV) by a trained healthcare provider. Both of theseside effectscould worsen depression and lead tolife-threateningconsequences. Injectafer is approved to treat iron deficiency anemia (IDA). Some may be a better fit for you than others. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. Its FDA-approved to treat iron deficiency anemia (IDA) in adults. Hes an expert in genetic testing, genetic analysis, andprecision medicine. After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. Injectafer may not be right for you if you have certain medical conditions or other factors affecting your health. On the other hand, some people may have a poor appetite that goes away when their anemia is treated. However, consuming large amounts of alcohol can actually cause anemia in some people. . The researchers found that compared with their hemoglobin level before the study: But the actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. An LSD comedown is when the mental and hallucinatory effects have worn . Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. As a result, you may not make as much EPO as usual. In the study, peoples hemoglobin level was measured to check for improvement in their anemia. Its not known how common delayed allergic reaction might be in other people using Injectafer. Usually, when drugs may cause an immune system reaction like this, its a concern with your first dose of the drug. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Venofer. signs of inflammation in the lining of your stomach --pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. Its responsible for carrying oxygen throughout your body. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Very bad and sometimes deadly allergic side effects have rarely happened. Excessive amounts of Venofer may lead to a condition called iron overload, which may be harmful. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. This medicine may cause serious types . These lists contain examples of serious side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). treatment schedule in further detail. If you would like to report to the FDA a side effect youve had with Injectafer, you can do so through MedWatch. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. So you wont pick up this medication from a pharmacy. And if you dont have an allergic reaction to your first dose of a drug, its typically safe to assume you wont have an allergic reaction to doses that follow. Follow all instructions closely. Some people are simply allergic to an active ingredient in the medication, so the body responds undesirably. Your doctor will recommend whether you should stop taking your multivitamin or any other supplements. Get emergency medical help if you have signs of an allergic reaction to Venofer: hives, rash, itching; feeling light-headed; difficulty breathing; swelling of your face, lips, tongue, or throat. But you kidneys need iron in order to make EPO. It is important to get each dose of this medication as scheduled. And these two doses need to be separated by at least 7 days. There may be risks to the mother and fetus associated with untreated IDA in pregnancy. How long does iron infusion stay in your system? If you have questions about the best diet for you during Injectafer treatment, talk with your doctor. This site is intended for use only by US patients. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The Food and Drug Administration (FDA) approves prescription drugs such as Injectafer to treat certain conditions. Storage Condition Store in a cool and dry place protected from light. Weight changes may be due to symptoms of anemia improving. Details. While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. Together, they can recommend ways to help you manage a body weight thats healthy for you.